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7BIO

A caspase- independent nonapoptotic cell death inducer and an inflammasome activator
Catalog #: 9690
SKU-Size Size Price Qty
9690-5 5 mg
$125.00
9690-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 7-Bromoindirubin-3'-oxime
Appearance Dark red solid
CAS # 916440-85-2
Molecular Formula C₁₆H₁₀BrN₃O₂
Molecular Weight 356.2
Purity ≥98% by NMR
Solubility DMSO
SMILES C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=C(C4=NC3=O)Br)NO
InChi InChI=1S/C16H10BrN3O2/c17-10-6-3-5-9-12(16(21)19-13(9)10)15-14(20-22)8-4-1-2-7-11(8)18-15/h1-7,18,20,22H
InChi Key MGVCNALPOHOEQM-UHFFFAOYSA-N
PubChem CID 11846148
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. In addition, 7BIO is a necrosis inducer and inflammasome activator. Also a potent inhibitor of Aurora kinase B and C.


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