5-Lipoxygenase, Active, Human Recombinant

Non-heme iron-containing dioxygenases
Catalog #: P1373 | abID:

Product Details

Alternate Name ALOX5, 5-LOX, Arachidonate 5-lipoxygenase
Gene Symbol ALOX5
Gene ID 240
Accession # P09917
Source E. coli
Physical Form Description Liquid
Molecular Weight 68.3 kDa (1-579 aa + N-terminal His Tag)
Purity by SDS-PAGE ≥95%
Specific Activity ≥ 100 µU/mg
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Lipoxygenases are non-heme iron-containing dioxygenases. These enzymes convert unsaturated fatty acids to epoxides, such as leukotrienes from arachidonic acid. They play an important role in cell proliferation, differentiation and inflammation; and have been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer.

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