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5-Fluorouridine

A ribonucleotide metabolite of 5-Fluorouracil with anticancer activity
Catalog #: B3149
SKU-Size Size Price Qty
B3149-100 100 mg
$60.00
B3149-500 500 mg
$235.00
More Sizes Get Quote

Product Details

Alternate Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fur; 1-(b-D-Ribofuranosyl)-5-fluorouracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; Furd
Appearance White to off-white powder
CAS # 316-46-1
Molecular Formula C₉H₁₁FN₂O₆
Molecular Weight 262.19
Purity ≥ 98%
Solubility ~50 mg/ml in water
SMILES C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F
InChi InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChi Key FHIDNBAQOFJWCA-UAKXSSHOSA-N
PubChem CID 9427
MDL Number MFCD00036832
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

5-Fluorouridine is a ribonucleotide metabolite of 5-Fluorouracil. It is cytotoxic and inhibits rRNA synthesis in human colon carcinoma cells. It exhibits cytotoxic effect on lymphoma cells with an IC₅₀ of 2 nM.


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