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5-Fluorouracil

An anticancer agent
Catalog #: B1519

In stock

SKU-Size Size Price Qty
B1519-1G 1 g
$55.00
B1519-5G 5 g
$145.00
More Sizes Get Quote

Product Details

Alternate Name 5-Fluoro-2,4-(1H,3H)-pyrimidinedione; 5-FU
Appearance White solid
CAS # 51-21-8
Molecular Formula C₄H₃FN₂O₂
Molecular Weight 130.08
Purity ≥98% by HPLC
Solubility DMSO (>10 mg/ml)
SMILES C1=C(C(=O)NC(=O)N1)F
InChi InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChi Key GHASVSINZRGABV-UHFFFAOYSA-N
PubChem CID 3385
MDL Number MFCD00006018
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

5-Fluorouracil (5-FU) is an anticancer agent that gets metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.


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