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5-Azacytidine

A DNA methyltransferase inhibitor
Catalog #: 1854
SKU-Size Size Price Qty
1854-50 50 mg
$60.00
1854-250 250 mg
$150.00
More Sizes Get Quote

Product Details

Alternate Name 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin
Appearance White to off-white solid
CAS # 320-67-2
Molecular Formula C₈H₁₂N₄O₅
Molecular Weight 244.2
Purity >95% by HPLC
Solubility AcOH: H₂O (1:1) (5 mg/ml)
SMILES C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
InChi InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)
InChi Key NMUSYJAQQFHJEW-UHFFFAOYSA-N
PubChem CID 1805
MDL Number MFCD00006539
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent growth inhibitor and cytotoxic agent; a potent DNA methyltransferase inhibitor. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes. Also recently shown to increase reprogramming efficiency of stem cells 10-fold.


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