Product Details
| Alternate Name | 4-HNE |
|---|---|
| Appearance | Liquid |
| Formulation | In Ethanol (10 mg/ml) |
| CAS # | 75899-68-2 |
| Molecular Formula | C₉H₁₆O₂ |
| Molecular Weight | 156.22 |
| Purity | ≥98% |
| SMILES | CCCCCC(C=CC=O)O |
| InChi | InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+ |
| InChi Key | JVJFIQYAHPMBBX-FNORWQNLSA-N |
| PubChem CID | 5283344 |
| MDL Number | MFCD00211020 |
| Handling | Protect from air |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
4-hydroxynonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-HNE is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. It also inhibits Sirtuin 3 (SIRT3) via thiol-specific modification.
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