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4-CPPC

A pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) inhibitor
Catalog #: B3278
SKU-Size Size Price Qty
B3278-1 1 mg
$95.00
B3278-5 5 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid 4CPPC
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 29553-70-6
Molecular Formula C₁₄H₉NO₆
Molecular Weight 287.23
Purity ≥98% by HPLC
Solubility DMSO
SMILES O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
InChi InChI=1S/C14H9NO6/c16-12(17)8-3-1-2-7(4-8)9-5-11(14(20)21)15-6-10(9)13(18)19/h1-6H,(H,16,17)(H,18,19)(H,20,21)
InChi Key O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
PubChem CID 893698
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

4-CPPC is a potent, reversible and selective small molecule inhibitor of the pro-inflammatory protein macrophage migration inhibitory factor-2 (a.k.a. MIF-2 or D-DT) (IC50 = 27 µM). 4-CPPC displays17-fold selectivity for MIF-2 versus MIF-1. MIF-2 is member of the MIF cytokine superfamily.


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