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An inhibitor of PARP
Catalog #: B3134
SKU-Size Size Price Qty
B3134-10 10 mg
B3134-50 50 mg
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Product Details

Alternate Name 6-aminobenzo[de]isoquinoline-1,3-dione; 4-Amino-1,8-naphthalimide; 4-Aminonaphthalene-1,8-dicarboximide; 7-Amino-3-hydroxy-1H-benzo[de]isoquinolin-1-one; 4-ANI
Appearance Orange powder
CAS # 1742-95-6
Molecular Formula C₁₂H₈N₂O₂
Molecular Weight 212.2
Purity ≥ 95%
Solubility ~1 mg/ml in DMSO
InChi InChI=1S/C12H8N2O2/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(15)14-12(8)16/h1-5H,13H2,(H,14,15,16)
PubChem CID 1720
MDL Number MFCD00006921
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


4-Aminonaphthalimide is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP with an IC₅₀ of 180 nM. It inhibits radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation.

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