Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

4-Aminonaphthalimide

An inhibitor of PARP
Catalog #: B3134
SKU-Size Size Price Qty
B3134-10 10 mg
$60.00
B3134-50 50 mg
$240.00
More Sizes Get Quote

Product Details

Alternate Name 6-aminobenzo[de]isoquinoline-1,3-dione; 4-Amino-1,8-naphthalimide; 4-Aminonaphthalene-1,8-dicarboximide; 7-Amino-3-hydroxy-1H-benzo[de]isoquinolin-1-one; 4-ANI
Appearance Orange powder
CAS # 1742-95-6
Molecular Formula C₁₂H₈N₂O₂
Molecular Weight 212.2
Purity ≥ 95%
Solubility ~1 mg/ml in DMSO
SMILES C1=CC2=C(C=CC3=C2C(=C1)C(=O)NC3=O)N
InChi InChI=1S/C12H8N2O2/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(15)14-12(8)16/h1-5H,13H2,(H,14,15,16)
InChi Key SSMIFVHARFVINF-UHFFFAOYSA-N
PubChem CID 1720
MDL Number MFCD00006921
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

4-Aminonaphthalimide is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP with an IC₅₀ of 180 nM. It inhibits radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.