Product Details
| Alternate Name | TNFRSF9, CD137 antigen, T-cell antigen ILA |
|---|---|
| Gene Symbol | TNR9 |
| Gene ID | 3604 |
| Accession # | Q07011 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized with no additives |
| Molecular Weight | 17.8 kDa |
| Purity by SDS-PAGE | ≥98% |
| Purity by | ≥98% |
| Endotoxin Level | <0.1 ng/μg |
| Biological Activity | Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 µg for both 4-1BBL and 4-1BBR. |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Recombinant human 4-1BBR is a 17.8 kDa protein containing 167 amino acid residues of extraCellular domain of 4-1BBR without signal peptide (Gene accession # NP_001552).
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