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3-Methyladenine

A specific autophagy inhibitor
Catalog #: 2249
SKU-Size Size Price Qty
2249-25 25 mg
$55.00
2249-100 100 mg
$185.00
More Sizes Get Quote

Product Details

Alternate Name 3-Methyl-3H-purin-6-amine; 3-MA; NSC 66389
Appearance White solid
CAS # 5142-23-4
Molecular Formula C₆H₇N₅
Molecular Weight 149.15
Purity ≥98%
Solubility DMSO (50 mM)
SMILES CN1C=NC(=C2C1=NC=N2)N
InChi InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChi Key FSASIHFSFGAIJM-UHFFFAOYSA-N
PubChem CID 1673
MDL Number MFCD00010531
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Commonly used as a specific inhibitor of autophagic sequestration. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).


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