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3-Cyano-7-ethoxycoumarin

A fluorogenic substrate for cytochrome P450
Catalog #: B3133
SKU-Size Size Price Qty
B3133-10 10 mg
$70.00
B3133-50 50 mg
$280.00
More Sizes Get Quote

Product Details

Alternate Name 7-ethoxy-2-oxochromene-3-carbonitrile; 7-ethoxy-2-oxo-2h-chromene-3-carbonitrile; 2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-
Appearance Yellow powder
CAS # 117620-77-6
Molecular Formula C₁₂H₉NO₃
Molecular Weight 215.2
Purity ≥ 98% (HPLC)
Solubility ~10 mg/ml in DMSO
SMILES CCOC1=CC2=C(C=C1)C=C(C(=O)O2)C#N
InChi InChI=1S/C12H9NO3/c1-2-15-10-4-3-8-5-9(7-13)12(14)16-11(8)6-10/h3-6H,2H2,1H3
InChi Key YAFGHMIAFYQSCF-UHFFFAOYSA-N
PubChem CID 164045
MDL Number MFCD00467359
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

3-Cyano-7-ethoxycoumarin is a fluorogenic substrate for cytochrome P450. It is metabolized to 3-cyano-7-hydroxycoumarin with an excitation/emission maxima of 408/450 nm, respectively. It can be used to quantify the activity of cytochrome P450-dependent mixed function oxidase.


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