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3-Bromo-7-nitroindazole

A potent nitric oxide synthase (NOS) inhibitor
Catalog #: 2361

In stock

SKU-Size Size Price Qty
2361-10 10 mg
$85.00
2361-50 50 mg
$325.00
More Sizes Get Quote

Product Details

Alternate Name 3-​bromo-​7-​nitro-​1H-​indazole
Appearance Light brown solid
CAS # 74209-34-0
Molecular Formula C₇H₄BrN₃O₂
Molecular Weight 242.03
Purity ≥98%
Solubility DMSO (~ 25 mg/ml) or EtOH (~12 mg/ml)
SMILES C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br
InChi InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)
InChi Key NFSTZPMYAZRZPC-UHFFFAOYSA-N
PubChem CID 1649
MDL Number MFCD00159910
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A more potent inhibitor of nNOS than 7-nitroindazole (Cat. No. 2360) in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.


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