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A thyroid hormone
Catalog #: B2017

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SKU-Size Size Price Qty
B2017-5 5 mg
B2017-25 25 mg
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Product Details

Alternate Name O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Liothyronine, T3; Reverse T3
Appearance Off-white solid
CAS # 5817-39-0
Molecular Formula C₁₅H₁₂I₃NO₄
Molecular Weight 650.97
Purity ≥95%
Solubility DMSO (30 mg/ml)
InChi InChI=1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)/t12-/m0/s1
PubChem CID 644280
MDL Number MFCD00036864
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


3,3',5’-Triiodo-L-thyronine (Reverse T3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3',5-triiodo-L-thyronine.  Reverse T3 positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation.

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