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2-Methoxyestradiol

An angiogenesis inhibitor
Catalog #: 2166

In stock

SKU-Size Size Price Qty
2166-5 5 mg
$65.00
2166-25 25 mg
$215.00
More Sizes Get Quote

Product Details

Alternate Name 2-​methoxy-​estra-​1,​3,​5(10)-​triene-​3,​17β-​diol; 2-Hydroxyestradiol 2-methyl ether; NSC659853; 2-ME2; Panzem
Appearance White to off-white solid
CAS # 362-07-2
Molecular Formula C₁₉H₂₆O₃
Molecular Weight 302.41
Purity ≥98%
Solubility DMSO (10 mg/ml) or EtOH (10 mg/ml)
SMILES CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O
InChi InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12?,13?,15?,18-,19-/m0/s1
InChi Key CQOQDQWUFQDJMK-WRWXEFHESA-N
PubChem CID 16760554
MDL Number MFCD00010489
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

2-Methoxyestradiol (2-ME) is major estradiol metabolite that acts as a potent inhibitor of endothelial cell proliferation and angiogenesis. It displays little affinity for classical estrogen receptors.


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