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An inhibitor of voltage-gated proton channel Hv1
Catalog #: B3130
SKU-Size Size Price Qty
B3130-100 100 mg
B3130-500 500 mg
More Sizes Get Quote

Product Details

Alternate Name 2GBI; 2-(1H-benzimidazol-2-yl)guanidine; (benzimidazol-2-ylamino)methanamidine
Appearance Off-white powder
CAS # 5418-95-1
Molecular Formula C₈H₉N₅
Molecular Weight 175.19
Purity ≥ 95%
Solubility ~50 mg/ml in DMSO
InChi InChI=1S/C8H9N5/c9-7(10)13-8-11-5-3-1-2-4-6(5)12-8/h1-4H,(H5,9,10,11,12,13)
PubChem CID 36149
MDL Number MFCD00005590
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


2-Guanidinobenzimidazole is an inhibitor of voltage-gated proton channel Hv1. It inhibits Hv1 proton conduction (10 μM-200 μM) by binding to the voltage-sensing domain. Inhibition of excessive Hv1 activity could be beneficial in ischemic stroke and cancer.

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