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2-Chloroadenosine

An adenosine receptor agonist
Catalog #: B3129
SKU-Size Size Price Qty
B3129-100 100 mg
$95.00
B3129-500 500 mg
$380.00
More Sizes Get Quote

Product Details

Alternate Name CADO; 2-CADO; 6-Amino-2-chloropurine riboside; (2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Appearance White to off-white powder
CAS # 146-77-0
Molecular Formula C₁₀H₁₂ClN₅O₄
Molecular Weight 301.69
Purity ≥ 98%
Solubility ~2.5 mg/ml in DMSO
SMILES C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)Cl)N
InChi InChI=1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
InChi Key BIXYYZIIJIXVFW-UUOKFMHZSA-N
PubChem CID 8974
MDL Number MFCD00005734
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

2-Chloroadenosine is an adenosine receptor agonist. It binds to adenosine A1, A2A, and A3 receptors with Ki values of 300, 80, and 1900 nM, respectively. It significantly decreases seizures in a rat model.


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