Product Details
| Cat # +Size | 3126-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | 14-3-3 |
| Host | Mouse |
| Antibody Type | Monoclonal |
| Isotype | Rabbit IgG |
| Accession # | P29310 |
| Gene ID | 36059 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | 100 µg (0.5 mg/ml) immunoaffinity purified mouse monoclonal antibody in PBS containing 1 mg/ml BSA and 1.5 mM sodium azide and 50% glycerol. |
| Purification | Affinity purified rabbit IgG |
| Species Reactivity | Human, Mouse, Rat, Pig, Monkey, Rabbit, Dog, Sheep, Bovine |
| Application | Western blot |
| Positive Control | Western Blot |
| Application & Usage | Western blot: 1-4 µg |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
The 14-3-3 proteins comprise a family of highly conserved acidic proteins which play a role in both signal transduction and the cell cycle by binding to and regulating several different proteins. The family of proteins is present in particularly high concentrations in mammalian brain and may be involved in the regulation of neuronal activity. The 14-3-3 proteins exist as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C.
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