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10058-F4

A c-Myc inhibitor
Catalog #: 2739
SKU-Size Size Price Qty
2739-5 5 mg
$85.00
2739-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Appearance Yellow solid
CAS # 403811-55-2
Molecular Formula C₁₂H₁₁NOS₂
Molecular Weight 249.35
Purity ≥98% by TLC
Solubility DMSO (60 mg/ml) or EtOH (20 mg/ml)
SMILES CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2
InChi InChI=1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+
InChi Key SVXDHPADAXBMFB-JXMROGBWSA-N
PubChem CID 1271002
MDL Number MFCD00758517
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

10058-F4 is a c-Myc inhibitor that inhibits the c-Myc-Max associationn and function. It prevents the growth of fibroblasts in a c-Myc-dependent manner. Downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. Induces cell cycle arrest, apoptosis and myeloid differentiation in human acute myeloid leukemia. 10058-F4 inhibits the MYCN/Max interaction leading to cell cycle arrest, apoptosis and neuronal differentiation in MYCN-amplified neuroblastoma cells.


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