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1,10-Phenanthroline

A metal chelator and inhibitor of metalloproteases
Catalog #: B3122
SKU-Size Size Price Qty
B3122-5G 5 g
$60.00
B3122-10G 10 g
$105.00
More Sizes Get Quote

Product Details

Alternate Name 2-Phenanthroline; 4,5-Diazaphenanthrene; o-Phenanthroline; 5,6-dihydro-1,10-phenanthroline
Appearance Off-white solid
CAS # 66-71-7
Molecular Formula C₁₂H₈N₂
Molecular Weight 180.2
Purity ≥ 98%
Solubility ~18 mg/ml in DMSO or Ethanol
SMILES C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1
InChi InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H
InChi Key DGEZNRSVGBDHLK-UHFFFAOYSA-N
PubChem CID 1318
MDL Number MFCD00011678
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

1,10-Phenanthroline is a metal chelator and inhibitor of metalloproteases. 1,10-Phenanthrine acts as a fungistatic against P. verrucosa (MIC = 0.8 μg/ml) and inhibits zinc-induced P. verrucosa metallo-type peptidase activity in a concentration-dependent manner. It reduces the expression of matrix metalloproteinase (MMP3) during chondrogenic differentiation of human chondrocytes.


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