Verteporfin

A photosensitizer and cancer stem cell inhibitor
Part #: B1583

Availability: In stock

SKU-Size Size Price Qty
B1583-5 5 mg
$145.00
B1583-25 25 mg
$575.00

Product Details

Alternate Name 4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester; BPD-MA
Appearance Black solid
CAS # 129497-78-5
Molecular Formula C₄₁H₄₂N₄O₈
Molecular Weight 718.79
SMILES CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C
InChi InChI=1S/C41H42N4O8/c1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)25(12-15-37(48)51-6)33(44-30)18-32-24(11-14-36(46)47)21(3)28(43-32)16-31(23)42-29/h9-10,13,16-19,38,42,44H,1,11-12,14-15H2,2-8H3,(H,46,47)/t38-,41+/m0/s1
InChi Key YTZALCGQUPRCGW-ZSFNYQMMSA-N
PubChem CID 5362420
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. More recently, Verteporfin has been identified as an inhibitor of YAP-TEAD interaction. Also suppresses cancer stem cell properties in vitro.
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