b-Secretase (BACE) is a membrane-bound aspartyl protease that cleaves the amyloid precursor protein to generate the N-terminus of the amyloid beta (ab) peptide. b-Secretase has been implicated to be an excellent target for anti-amyloid therapy for the treatment of Alzheimer’s disease. Finding inhibitors of b-secretase is one of the major goals of Alzheimer’s disease drug development. BioVision’s b-Secretase Fluorometric Assay Kit provides a convenient, nonradioactive system for detecting b-Secretase activity in biological and purified samples. The kit provides active b-secretase as the positive control, b-secretase inhibitor as the negative control, as well as the optimized substrate and buffers for convenient measurement of b-secretase activity in mammalian samples.

Product Cat. # Size Price (USD) Data Sheet Add to Cart
b-Secretase Fluorometric Assay Kit K360-100 100 assays $395.00 Product Data Sheet
b-Secretase Inhibitor I 7501-1 1 mg $195.00 Product Data Sheet
b-Secretase Inhibitor II 7502-1 1 mg $105.00 Product Data Sheet

Detection of b-Secretase Activity in the Presence and Absence of b-Secretase Inhibitor.

Related Antibodies Cat. # Size Price (USD) Data Sheet Add to Cart
b-Amyloid Polyclonal Antibody 3356-100 100 ug $225.00 Product Data Sheet
APP Polyclonal Antibody 6001-100 100 ug $225.00 Product Data Sheet
BACE/Asp2 Polyclonal Antibody 6101-100 100 ug $225.00 Product Data Sheet
BACE2/Asp1Polyclonal Antibody 6102-100 100 ug $225.00 Product Data Sheet

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