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Home » » Enzyme Inhibitors » Microtubule Inhibitors » 2213-25
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Thiocolchicine
A tubulin polymerization and microtubule assembly inhibitor

Catalog# Size Price    
2213-25 25 mg $250.00 Add to Cart
2213-55 mg$75.00Add to Cart

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Product Name: Thiocolchicine

Alternate Name/Synonyms: 10-Demethoxy-10-methylthiocolchicine; NSC 186301

Description: An antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor and axonal cytoskeleton modulator; apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.

Peptide Sequence: N/A

Appearance: Yellow solid

Formulation: N/A

CAS Number: 2730-71-4

Molecular Formula: C₂₂H₂₅NO₅S

Molecular Weight: 415.5

Purity: ³95% by NMR

Solubility:DMSO

Storage Temp.: -20°C

Shipping Conditions: gel pack

Handling: Protect from air and light

SMILES: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC

InChi: InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)

InChi Key: CMEGANPVAXDBPL-UHFFFAOYSA-N

PubChem CID: 546854

MDL Number: N/A

USAGE: For Research Use Only! Not For Use in Humans.

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