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Salinomycin Sodium

A cancer stem cell inhibitor
SKU: B1584

Availability: In stock

SKU-Size Size Price Qty
B1584-25 25 mg
$95.00
B1584-100 100 mg
$295.00

Details

Salinomycin is a polyether ionophore antibiotic that has recently been identified as an antitumor drug for several types of cancer stem cell (CSC) treatments. Salinomycin inhibits the migration and invasion of liver cancer stem cells (LCSCs) through the dephosphorylated FAK and ERK1/2 pathways.

Product Details

Alternate Name (R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((2S,5S,7R,9S,10S,12R,15R)-2-((2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-
Appearance White to of-white solid
CAS # 55721-31-8
Molecular Formula C₄₂H₆₉O₁₁. Na
Molecular Weight 772.98
Purity ≥850U/mg
Solubility DMSO (~5 mg/ml)
SMILES CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)[O-].[Na+]
InChi InChI=1S/C42H70O11.Na/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33;/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47);/q;+1/p-1/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-;/m0./s1
InChi Key YPZYGIQXBGHDBH-UZHRAPRISA-M
PubChem CID 23703990
MDL Number MFCD00036900
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.
$
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