siRNA Expression Vectors
BioVision offers small interfering RNA (siRNA) vectors targeting many important genes to study protein function in a wide range of cell types. Small interfering RNAs (siRNAs) are short, double-stranded RNA molecules that can target and degrade specific complementary mRNAs. The target gene-specific degradation is an effective means of gene suppression. BioVision's GeneBlocker pGB siRNA expression vectors are designed to provide efficient suppression of a target gene in cultured mammalian cells and in vivo. The pGB vector has been optimized for suppressing expression of target genes using the human U6 promotor (a RNA polymerase III promotor) which generates large amounts of siRNA in mammalian cells. The pGB vector provides neomycin resistance marker for the selection of stable cell lines, permitting long term suppression of the target gene. The negative control siRNA vector and pGB cloning vector for cloning in your own insert are also available.
- • Target Specific; Efficient Suppression Target Genes in Cultured Mammalian Cells and in vivo
- • Cloning Your Own siRNA Insert
- • Transient or Stable Transfections
siRNA Expression Vectors Product List