Autophagy comes from the words "auto"- self and "phagy"- destruction, a normal physiological process of cell degradation. It plays an important role in turnover of degraded proteins and cell organelles in order to generate new cells. This process is initiated during cellular stress and lack of nutrients, so cells can use its own building blocks for renewal.
Upon initiation of autophagy, targeted cellular constituents are sequestered in double-membraned vesicles called as the autophagosome which fuses with the lysosome where proteins are recycled or degraded. The three forms of autophagy: macroautophagy, microautophagy and chaperone assisted autophagy play distinct roles in this entire process.
To help advance research in this field BioVision has added a number of products to its portfolio.