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Home » » Epigenetics » Eraser Enzymes » Histone Deacetylases » HDAC Inhibitors » 1612-25
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Panobinostat (LBH589)
A HDAC inhibitor

Catalog# Size Price    
1612-25 25 mg $995.00 Add to Cart
1612-55 mg$325.00Add to Cart
1612-11 mg$105.00Add to Cart

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Product Name: Panobinostat (LBH589)

Alternate Name/Synonyms: LBH589, LBN-589, NVP-LBH590

Description: Panobinostat (LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The IC₅₀ values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.23±0.06, 283±29, 75±4, 47±5 and 89±12 nM, respectively. And to A2780 proliferation, IC₅₀ value is 4.6±1.8 nM.

Peptide Sequence: N/A

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 404950-80-7

Molecular Formula: C₂₁H₂₃N₃O₂

Molecular Weight: 349.43

Purity: ≥99% by HPLC

Solubility:DMSO

Storage Temp.: -20°C

Shipping Conditions: RT

Handling: Protect from air and moisture

SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO

InChi: InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+

InChi Key: FPOHNWQLNRZRFC-ZHACJKMWSA-N

PubChem CID: 6918837

MDL Number: MFCD09833242

USAGE: For Research Use Only! Not For Use in Humans.

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