Alternative Name: SELL , Lymphocyte adhesion molecule 1
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 69 of human L-Selectin
Gene ID: 6402
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5mg/ml) protein A purified rabbit anti-L-Selectin polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat
Application: Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage: Western blotting (0.5-4 µg/ml), immunoprecipitation (10-20 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes L-Selectin in human sample, and in a lesser extent to mouse, and rat samples.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin (also called ELMA-1) expressed on endothelial cells. L-Selectin (also called LECAM-1) is expressed on the majority of B and naïve T cells and on most monocytes, neurophils and eosinophils. P-Selectin (also called GMP-140) expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans.