Antibody Target: IRF

Alternative Name: Interferon regulatory factor 3

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Immunogen: Synthetic peptide of human IRF3

Accession#: Q14653

Gene ID: 3667

Appearance: Colorless liquid

Concentration: N/A

Formulation: 100 µL affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.

Purification: Affinity purified

Species Reactivity: human

Application: Western blot

Application & Usage: Western blotting (1:200 – 1:500). However, the optimal concentrations should be determined individually.

Storage Temp.: -20 °C

Shipping: gel pack

Background Descriptions: IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.

Handling: The antibody solution should be gently mixed before use.

Usage: For Research Use Only! Not to be used in humans.