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HG-9-91-01

A potent, selective, ATP-competitive, pan-SIK (salt-inducible kinases) inhibitor
Catalog #: B1849

Availability: In stock

SKU-Size Size Price Qty
B1849-1 1 mg
$115.00
B1849-5 5 mg
$455.00

Product Details

Alternate Name (Z)-N-(2,4-dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)carbamimidic acid
Appearance Crystalline solid
CAS # 1456858-58-4
Molecular Formula C₃₂H₃₇N₇O₃
Molecular Weight 567.68
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
InChi InChI=1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-14,19-21H,15-18H2,1-5H3,(H,36,40)(H,33,34,35)
InChi Key UYUHRKLITDJEHB-UHFFFAOYSA-N
PubChem CID 78357808
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

HG-9-91-01 is a potent, selective, ATP-competitive, pan-SIK (salt-inducible kinases) inhibitor with IC₅₀ values of 0.92 nM, 6.6n M and 9.6 nM for SIK1, SIK2, SIK3, respectively.


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