A potent and selective pan-TRK inhibitor
Catalog #: B1339

Availability: In stock

SKU-Size Size Price Qty
B1339-5 5 mg
B1339-25 25 mg

Product Details

Alternate Name (Z)-1-(3-((3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)amino)-4-methylphenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Appearance Solid
CAS # 1033769-28-6
Molecular Formula C₂₈H₂₁F₄N₅O₂
Molecular Weight 535.49
Purity >98% by HPLC
Solubility DMSO > 10 mM
SMILES CC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)C(=CC5=CC=CN5)C(=O)N4
InChi 1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-34H,1H3,(H,36,38)(H2,35,37,39)/b21-12-
PubChem CID 59397065
MDL Number MFCD24386809
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent and selective pan-TRK inhibitor, suppressing the activity of TrkA and TrkB with IC50 of 8 and 12 nM, respectively
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