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GDC-0084

A potent and selective inhibitor of Class I PI3K and mTOR
Catalog #: B1656

Availability: In stock

SKU-Size Size Price Qty
B1656-5 5 mg
$85.00
B1656-25 25 mg
$335.00

Product Details

Alternate Name GDC-0084, GDC0084; GDC 0084; RG-7666; RG 7666; RG7666; 5-[8,9-dihydro-6,6-dimethyl-4-(4-morpholinyl)-6H-[1,4]oxazino[4,3-e]purin-2-yl]-2-pyrimidinamine; 5-(6,6-dimethyl-4-morpholin-4-yl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl)pyrimidin-2-amine
Appearance Solid
CAS # 1382979-44-3
Molecular Formula C₁₈H₂₂N₈O₂
Molecular Weight 382.42
Purity >98%
Solubility DMSO
SMILES CC1(C2=NC3=C(N2CCO1)N=C(N=C3N4CCOCC4)C5=CN=C(N=C5)N)C
InChi InChI=1S/C18H22N8O2/c1-18(2)16-22-12-14(25-3-6-27-7-4-25)23-13(11-9-20-17(19)21-10-11)24-15(12)26(16)5-8-28-18/h9-10H,3-8H2,1-2H3,(H2,19,20,21)
InChi Key LGWACEZVCMBSKW-UHFFFAOYSA-N
PubChem CID 57384863
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GDC-0084 is a potent, selective inhibitor of Class I PI3K and mTOR with good penetration across the blood-brain barrier.
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