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Ertugliflozin

A potent and selective sodium-dependent glucose cotransporter 2(SGLT2) inhibitor
Catalog #: B1896

Availability: In stock

SKU-Size Size Price Qty
B1896-5 5 mg
$145.00
B1896-25 25 mg
$575.00

Product Details

Alternate Name (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-hydroxymethyl-6,8-dioxabicyclo(3.2.1)octane-2,3,4-triol; PF-04971729
Appearance Crystalline solid
CAS # 1210344-57-2 
Molecular Formula C₂₂H₂₅ClO₇
Molecular Weight 436.89
Purity ≥98% by HPLC
Solubility DMSO
SMILES CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl
InChi InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+,21-,22-/m0/s1
InChi Key MCIACXAZCBVDEE-CUUWFGFTSA-N
PubChem CID 44814423
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ertugliflozin is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2(SGLT2); increases the excretion of glucose with a 2,000-fold selectivity over SGLT1 (IC₅₀ = 0.877 and 1,960 nM, respectively, for human isoforms in vitro.


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