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Elesclomol (STA-4783)

A novel anticancer agent that displays oxidative stress induction, pro-apoptotic, and potential antineoplastic activities
Part #: B1815

Availability: In stock

SKU-Size Size Price Qty
B1815-5 5 mg
$115.00
B1815-25 25 mg
$455.00

Product Details

Alternate Name  N'1,N'3-dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide; STA4783
Appearance Crystalline solid
CAS # 488832-69-5 
Molecular Formula C₁₉H₂₀N₄O₂S₂
Molecular Weight 400.52
Purity ≥98% by HPLC
Solubility DMSO ( >20 mg/ml)
SMILES CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
InChi InChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)
InChi Key BKJIXTWSNXCKJH-UHFFFAOYSA-N
PubChem CID 300471
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Elesclomol is a novel anticancer agent that displays oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. The mechanism underlying the proapoptotic activity of elesclomol is through the induction of ROS (reactive oxygen species) and oxidative stress. Elesclomol rapidly induces ROS in cancer cells, generating a transcription profile characteristic of an oxidative stress response.
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