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Dihydrotanshinone I

An anticancer agent
Catalog #: B1903

Availability: In stock

SKU-Size Size Price Qty
B1903-5 5 mg
$95.00
B1903-25 25 mg
$375.00

Product Details

Alternate Name (1R)-1,6-dimethyl-1,2-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione; (-)-Dihydrotanshinone I, 15,16-Dihydrotanshinone I; DHT
Appearance Red solid
CAS # 87205-99-0
Molecular Formula C₁₈H₁₄O₃
Molecular Weight 278.3
Purity ≥98% by HPLC
Solubility EtOH (~ 1 mg/ml)
SMILES CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3C=CC=C4C
InChi InChI=1S/C18H14O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-7,10H,8H2,1-2H3
InChi Key HARGZZNYNSYSGJ-UHFFFAOYSA-N
PubChem CID 5316743
MDL Number MFCD28016070
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Dihydrotanshinone, isolated from Salvia miltiorrhiza (S. miltiorrhiza) is an effective anti-cardiovascular disease agent. It also induces apoptosis and inhibits proliferation of glioma cells. DHT induces growth inhibition and apoptosis of gastric cancer cells, involving activation of caspase proteins and the JNK/p38 signaling pathway.


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