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CZC-8004

A pan-specific kinase inhibitor
Catalog #: B1868

Availability: In stock

SKU-Size Size Price Qty
B1868-5 5 mg
$95.00
B1868-25 25 mg
$375.00

Product Details

Alternate Name N2-​[4-​(aminomethyl)​phenyl]​-​5-​fluoro-​N4-​phenyl-2,​4-​pyrimidinediamine
Appearance Off-white solid
CAS # 916603-07-1
Molecular Formula C₁₇H₁₆FN₅
Molecular Weight 309.3
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN
InChi InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)
InChi Key UKOHFWNBTUJMMN-UHFFFAOYSA-N
PubChem CID 15980598
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CZC-8004 is a pan-specific kinase inhibitor that binds to a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be coupled to sepharose via its amino side chain for affinity chromatography applications.
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