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CHIR-090

A potent, low, tight-binding inhibitor of LpxC
Catalog #: B1852

Availability: In stock

SKU-Size Size Price Qty
B1852-5 5 mg
$145.00
B1852-25 25 mg
$575.00

Product Details

Alternate Name N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide
Appearance Crystalline solid
CAS # 728865-23-4 
Molecular Formula C₂₄H₂₇N₃O5
Molecular Weight 437.5
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml)
SMILES CC(C(C(=O)NO)NC(=O)C1=CC=C(C=C1)C#CC2=CC=C(C=C2)CN3CCOCC3)O
InChi InChI=1S/C24H27N3O5/c1-17(28)22(24(30)26-31)25-23(29)21-10-8-19(9-11-21)3-2-18-4-6-20(7-5-18)16-27-12-14-32-15-13-27/h4-11,17,22,28,31H,12-16H2,1H3,(H,25,29)(H,26,30)/t17-,22+/m1/s1
InChi Key FQYBTYFKOHPWQT-VGSWGCGISA-N
PubChem CID 11546620
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CHIR-090 is a potent, low, tight-binding inhibitor of LpxC (UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase) (Ki = 4.0 nM). Antibacterial agent


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