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CGM097

A potent and selective MDM2 inhibitor
Part #: B1820

Availability: In stock

SKU-Size Size Price Qty
B1820-1 1 mg
$115.00
B1820-5 5 mg
$455.00

Product Details

Alternate Name (S)-1-(4-chlorophenyl)-7-isopropoxy-6-methoxy-2-(4-(methyl(((1r,4S)-4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl)methyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one
Appearance Crystalline solid
CAS # 1313363-54-0 
Molecular Formula C₃₈H₄₇ClN₄O₄ 
Molecular Weight 659.26
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC(C)OC1=C(C=C2CC(=O)N(C(C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC
InChi InChI=1S/C38H47ClN4O4/c1-25(2)47-35-22-33-28(20-34(35)46-5)21-36(44)43(38(33)27-8-10-29(39)11-9-27)32-16-14-30(15-17-32)41(4)23-26-6-12-31(13-7-26)42-19-18-40(3)37(45)24-42/h8-11,14-17,20,22,25-26,31,38H,6-7,12-13,18-19,21,23-24H2,1-5H3/t26?,31?,38-/m0/s1
InChi Key CLRSLRWKONPSRQ-CPOWQTMSSA-N
PubChem CID 53240420
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CGM097 is a potent and selective MDM2 inhibitor; an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity.
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