Casticin

An anticancer agent
Part #: B1575

Availability: In stock

SKU-Size Size Price Qty
B1575-5 5 mg
$125.00
B1575-25 25 mg
$495.00

Product Details

Alternate Name 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one; Vitexicarpin
Appearance Yellow solid
CAS # 479-91-4
Molecular Formula C₁₉H₁₈O₈
Molecular Weight 374.34
Purity ≥98% by HPLC
Solubility DMSO (10 mg/ml) or EtOH (1 mg/ml)
SMILES COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O
InChi InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
InChi Key PJQLSMYMOKWUJG-UHFFFAOYSA-N
PubChem CID 5315263
MDL Number MFCD00210481
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis. It displays anticancer activities including induction of cell apoptosis in human cancer cells. Casticin impairs cell migration and invasion of mouse melanoma B16F10 cells via PI3K/AKT and NF-κB signaling pathways.
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