BMP-14/GDF-5, human recombinant

A regulator of cell growth and differentiation
Part #: 4667

Availability: In stock

SKU-Size Size Price Qty
4667-10 10 μg
$80.00
4667-50 50 μg
$190.00
4667-1000 1 mg
$1,500.00

Product Details

Alternate Name Cartilage-derived morphogenetic protein-1, Cartilage-Derived Morphogenetic Protein-1, CDMP-1, LAP4, SYNS2, Radotermin, CDMP1, GDF5, Growth differentiation factor 5, BMP-14
Gene Symbol GDF5
Gene ID 8200
Accession # P43026
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives
Molecular Weight 13.6 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED50 as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is 1-5 µg/ml
Reconstitution Instructions Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

GDF-5 acts as an inhibitor of nerve tissue growth. It is produced as a homodimer, non-glycosylated polypeptide chain containing 2 X 117 amino acids with a molecular weight of 26.8 kDa. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro- Leu- Thr and added the Lys.
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