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Atazanavir

A potent inhibitor of HIV protease
Catalog #: B1901

Availability: In stock

SKU-Size Size Price Qty
B1901-5 5 mg
$115.00
B1901-25 25 mg
$455.00

Product Details

Alternate Name Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
Appearance White to off-white solid
CAS # 198904-31-3
Molecular Formula C₃₈H₅₂N₆O₇
Molecular Weight 704.86
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC
InChi InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
InChi Key AXRYRYVKAWYZBR-GASGPIRDSA-N
PubChem CID 148192
MDL Number MFCD08435966
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Atazanavir is a potent inhibitor of HIV protease (Ki of 2.66 nM). Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells.


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