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Anti-PRMT6 Antibody (2C3-F1-G1)

Monoclonal antibody to detect Eg5
Catalog #: A1310

Availability: In stock

$265.00

Product Details

Cat # +Size A1310-100
Size 100 µg
Antibody Target PRMT6
Alternate Name HRMT1L6
Host Human
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen Recombinant human PRMT6 protein fragments expressed in E.coli
Accession # Q96LA8
Gene ID 55170
Appearance Colorless liquid
Formulation In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Purification Affinity purified
Species Reactivity Human
Application WB, IF, IHC
Positive Control WB: HeLa and 293T cell lysate; IF: Hela cells; IHC: human breast cancer tissue
Application & Usage WB; 1:1000; IF; 1:300; IHC
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.


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