Anti-PD-1 (Pembrolizumab), Humanized Antibody

Monoclonal human IgG1 antibody against human PD-1
Catalog #: A1306

Availability: In stock

$295.00

Product Details

Cat # +Size A1306-100
Size 100 µg
Antibody Target PD-1
Alternate Name Keytruda, PD-1
Host Human
Antibody Type Monoclonal
Isotype Human IgG4
Immunogen Human programmed cell death 1 receptor (PD1)
Accession # Q02242
Gene ID 18566
Appearance Colorless liquid
Formulation In phosphate buffered saline, pH 7.5
Purification Affinity purified
Species Reactivity Human
Application Neutralization, ELISA
Application & Usage Neutralization: 0.1-1 μg/ml, ELISA: 1 μg/ml
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
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