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AMG-900

A highly sensitive and orally bioavailable inhibitor of Aurora Kinase
Catalog #: B1343

Availability: In stock

SKU-Size Size Price Qty
B1343-5 5 mg
$325.00
B1343-25 25 mg
$1,375.00

Product Details

Alternate Name N-[4-[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxyphenyl]-4-(4-methylthiophen-2-yl)phthalazin-1-amine
Appearance Solid
CAS # 945595-80-2
Molecular Formula C₂₈H₂₁N₇OS
Molecular Weight 503.58
Purity >98%
Solubility DMSO > 10 mM
SMILES CC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=C6)N
InChi 1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-25)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)33-23/h2-16H,1H3,(H,32,35(H2,29,31,33)
InChi Key IVUGFMLRJOCGAS-UHFFFAOYSA-N
PubChem CID 24856041
MDL Number MFCD18633194
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AMG-900 is a highly sensitive and orally bioavailable inhibitor of Aurora Kinase with IC50 values of 5 nmol/L


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