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Acalisib

A PI3Kδ inhibitor
Catalog #: B1666

Availability: In stock

SKU-Size Size Price Qty
B1666-5 5 mg
$85.00
B1666-25 25 mg
$335.00

Product Details

Alternate Name Acalisib; GS-9820; GS 9820; GS9820; (S)-2-(1-((9H-purin-6-yl)amino)ethyl)-6-fluoro-3-phenylquinazolin-4(3H)-one; 6-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)ethyl]quinazolin-4-one
Appearance Solid
CAS # 870281-34-8
Molecular Formula C₂₁H₁₆FN₇O
Molecular Weight 401.4
Purity >98%
Solubility DMSO
SMILES CC(C1=NC2=C(C=C(C=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
InChi InChI=1S/C21H16FN7O/c1-12(27-19-17-18(24-10-23-17)25-11-26-19)20-28-16-8-7-13(22)9-15(16)21(30)29(20)14-5-3-2-4-6-14/h2-12H,1H3,(H2,23,24,25,26,27)/t12-/m0/s1
InChi Key DOCINCLJNAXZQF-LBPRGKRZSA-N
PubChem CID 11618268
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Acalisib (GS-9820) is a potent and selective inhibitor of PI3Kδ with IC50 value of 12.7 nM.
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